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The Risks and Side Effects of Bone Cell Therapy
25th May 2023
If you or someone you know has ever been affected by the bone disease in the past, most often you may have been advised pain medication, rest and physiotherapy to manage the bone disease, or major surgery that involves the partial or total replacement of a joint or in some cases bone grafting.
Bone diseases like osteoporosis, osteoarthritis, and osteonecrosis are chronic disorders that progressively worsen without intervention.
The biggest challenge faced by the medical community is that in spite of the best efforts to heal bone diseases using conventional methods, the treatment turns out unsuccessful or insufficient.
In the case of osteoporosis, doctors often recommend different medications that could slow down the progress of osteoporosis as well as lifestyle changes that can help protect the bone from unnecessary stress. A person usually has to live with the condition, managing the progressive deterioration of bone mass and density with various medications that include hormone therapies, etc. The results can vary vastly from person to person and usually works on a trial basis with the doctor closely monitoring the response to each medicative therapy.
Early stages of osteoarthritis may be treated with physiotherapy and diet and even arthroscopic surgery to remove loose ends of flapping cartilage. But cartilage continues to deteriorate generally in the case of osteoarthritis. In this case, the joint needs to undergo a replacement surgery where a metal or ceramic joint replaces the affected joint. Osteoarthritis most commonly affects the knees. Joint replacement surgery consists of a major surgery that has a considerable amount of risk that only increases with a patient that may also be aged and suffering from other problems. Osteonecrosis also requires joint replacement surgery. As osteonecrosis also known as avascular necrosis, usually affects the hip, a hip replacement surgery requires much consideration of the patient’s existing status of health and age. Patients that are young may even require remission surgery after 10-15 years.
Autologous grafting has been considered the most recommended treatment procedure for most bone defects. However, the procedure has inherent limitations to its application. These unsatisfactory results have pushed the medical community to seek treatments that can provide better results at least in circumstances of general good health.
There has been a need for a scientific leap in treatment methods of common bone disorders that can make prudent investments in treatment, as well as offer better chances of desired results. This is exactly what advancements in bone cell therapy have sought to achieve.
Bone cell therapy consists of extracting the patient’s own bone marrow cells to develop and implant live culture bone-forming cells called osteoblasts to an affected area. Live culture is developed by tissue engineering under laboratory conditions. Case studies have been published on the commercially available bone cell therapy called OSSGROW® which consists of the implantation of autologous adult live cultures osteoblasts derived from mesenchymal stem cells extracted out of bone marrow cells. This helps restore bone form and restore function and reduces pain in 90% of cases. Even in cases of osteoporosis or osteonecrosis, bone cell therapy can slow down progression very effectively giving the patient many more years of mobility without pain.
Every treatment option for bone disorders such as osteoporosis, osteoarthritis, and osteonecrosis has risks and conditions for desired results. None of these options come with a clean chit or guarantee and each treatment option needs to be individually weighed out on a case-to-case basis depending on the patient’s overall health, lifestyle, age, and any other pre-existing medical conditions. Likewise, bone cell therapy has several factors that need to be considered before, during, and after treatment.
First and foremost, anybody considering bone cell therapy must opt for a licensed, authorized, and reputable bone cell therapy that can be delivered by a competent and well-established medical facility. Unauthorized treatments are a big risk that may seem to save money but will end up providing no results, or worse, negatively impacting health with zero commitment. Ensure you take the time to research the treatment option provided to you and choose the option that has been proven in the market.
Choose India-based Regrow Biosciences’ OSSGROW® Bone Cell Therapy which has been the first to receive market authorization and commercial sale license since 2017. Contact Regrow Biosciences to learn more.
Secondly, the most commonly cited risk of most procedures involving implantation is the risk of infection. Your doctor will be monitoring the site of implantation for infection closely. However, you may experience some level of discomfort in the short term like pain, numbness, or even a tingling sensation.
While 90% of cases that have undergone bone cell therapy have reported improvement in pain symptoms and mobility and function, there are cases that have not seen desired results and may have even opted for surgery later. Some considerations that may influence the efficacy of treatment are discussed below:
1) After the procedure for bone cell therapy, one month of bed rest followed by a month of passive exercise is essential. While the procedure does not involve major surgery, bone cell therapy requires time to take effect and reverse the effects of deterioration.
2) Osteonecrosis can be brought on by steroid use and alcoholism. While bone cell therapy can work well in the majority of such cases, continuing the use of steroids and alcohol can reverse the effects of bone cell therapy.
3) In the long term, patients are still recommended to follow a healthy lifestyle with a good diet, exercise, and a general level of activity to maintain good bone health.
Bone disorders such as osteoarthritis and osteonecrosis conventionally have been treated with surgery such as joint replacement surgery. Some bone defects have also been known to use autologous bone grafting to some notable level of success. Osteoporosis has always been challenging to treat with medication being a common treatment to slow down the progression of the disease. In view of the limitations that conventional treatment inherently holds and the need for treatments that can show better prospects for desired results, bone cell therapy is an option to consider. Bone cell therapy uses the patient’s own cells to develop a live culture of bone-forming cells that are then implanted into the affected area to help form or repair bone mass and form and restore function. Every treatment is not without its risks and conditions. Bone cell therapy from an authorized company is the primary requirement to avoid ill effects. Infection at the site of implantation may be seen. Additionally, the patient is expected to take into consideration rest when required and adopt a healthy lifestyle to help support the effects of bone cell therapy.
Is bone cell therapy a safe treatment?
Bone cell therapy is a safe and effective treatment that uses the patient’s own cells and with a very very low chance of rejection by the body. As long as bone cell therapy from a reputed and authorized biotech company has been used, there is no need to worry about the safety of bone cell therapy.
Is bone cell therapy available in India?
Yes. Regrow Biosciences is a market-authorized and commercially licensed biotech company based in India providing bone cell therapy, cartilage cell therapy and epithelial cell therapy.
Can bone cell therapy cure arthritis?
Bone cell therapy can be used to cure osteoarthritis with an efficacy rate of 90%.
Who should I consult to get bone cell therapy as a treatment option?
Most major hospitals and orthopedic doctors are familiar with bone cell therapy. If you want to know doctors in your area that you can consult to receive bone cell therapy, contact Regrow Biosciences and we can provide options that best suit you.
What is the risk of infection from bone cell therapy?
There is a small risk of infection at the site of implantation. Your doctor will be monitoring closely for any infection and will be able to treat it fast enough before it becomes a problem. There may be slight discomfort at the site of implantation in the short term as well.